Real-world database evaluation of drug-associated vitreous opacities and machine learning for clinical interpretability
This first systematic real-world evaluation of VO-related adverse drug reactions identifies high-risk drugs, susceptible populations, and onset patterns, thus offering guidance for preventive medication strategies. The BAG model showed higher sensitivity in real-world analysis, suggesting potential for further research in VO and floater prevention and treatment.
Authors
- Bo Yan (ORCID: https://orcid.org/0000-0001-5038-9008)
- Yuwen Liu (ORCID: https://orcid.org/0000-0002-7135-7053)
- Changsheng Xu (ORCID: https://orcid.org/0000-0001-8343-9665)
- Jiaoyue Hu
- Ke Mi Feng
- Shi-nan Wu
- Zuguo Liu
- Wenying Guan
- Caihong Huang
- Jingyao Lv
Institutions
- Xiamen University (CN)
- First Affiliated Hospital of University of South China (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fcell.2025.1699669
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China