Demonstrating the value for money of implementing evidence-based treatment: the case for further investment in magnesium sulphate as a neuroprotectant for preterm births

The case of MgSO<sub>4</sub> treatment for preterm birth illustrates how sub-optimal implementation of evidence-based interventions can be associated with high opportunity costs measured as INMB forgone. This approach provides valuable quantification of the value for money of future QI programmes to improve the implementation of these interventions.

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Publication Details

Journal
Frontiers in Health Services
Published
2026-01-12
DOI
https://doi.org/10.3389/frhs.2025.1655385
Primary Topic
Preterm Birth and Chorioamnionitis
Type
article
Field-Weighted Citation Impact
0.00

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article

Demonstrating the value for money of implementing evidence-based treatment: the case for further investment in magnesium sulphate as a neuroprotectant for preterm births

Carlos Sillero‐Rejon, K LUYT, Hannah B Edwards, David Odd et al.
Frontiers in Health Services
Preterm Birth and Chorioamnionitis
article

Demonstrating the value for money of implementing evidence-based treatment: the case for further investment in magnesium sulphate as a neuroprotectant for preterm births

Carlos Sillero‐Rejon, K LUYT, Hannah B Edwards, David Odd, Sabi Redwood, Hugh McLeod, Frank de Vocht, Christalla Pithara-McKeown, William Hollingworth, Brent C. Opmeer
article en

Abstract

The case of MgSO<sub>4</sub> treatment for preterm birth illustrates how sub-optimal implementation of evidence-based interventions can be associated with high opportunity costs measured as INMB forgone. This approach provides valuable quantification of the value for money of future QI programmes to improve the implementation of these interventions.

Frontiers in Health ServicesVol. 5
Cardiff and Vale University Health Board (GB), University Hospitals Bristol NHS Foundation Trust (GB), University of Bristol (GB), Dutch Expert Centre for Screening (NL), St Michael's Hospital (GB), Cardiff University (GB)
University Hospitals Bristol NHS Foundation Trust, National Institute for Health and Care Research, Department of Health and Social Care, Oxford Academic Health Science Network, National Institute for Health Research Applied Research Collaboration West
Peace, Justice and strong institutions
Openalex Percentile: Top 90%
Preterm Birth and Chorioamnionitis
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Demonstrating the value for money of implementing evidence-based treatment: the case for further investment in magnesium sulphate as a neuroprotectant for preterm births — Carlos Sillero‐Rejon, K LUYT, et al. · Frontiers in Health Services (2026) | TGRS Research Map | TGRS