Antigenic assessment for the β2-glycoprotein I/Platelet factor 4 complex in thrombotic patients with antiphospholipid syndrome
This study demonstrated the presence of anti-β2-GPI/PF4 in patients with APS, where it may be involved in the mechanism underlying the hypercoagulable state and correlated with a greater risk of developing thrombosis, especially in the young population.
Authors
- Gloria Riitano
- M. Sorice
- Antonio Sili Scavalli (ORCID: https://orcid.org/0000-0003-2534-4224)
- Giuseppe Tripodi
- S. Mancuso
- F. M. Ucci (ORCID: https://orcid.org/0000-0002-3618-2243)
- V. Manganelli
- Francesca Villani
- M. De Michele
- A. Capozzi
- Cristiano Alessandri
- Luca Rapino
- Fabrizio Conti
Institutions
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1674181
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sapienza Università di Roma