Transcriptome analysis and RT-qPCR validation of mitophagy-related key genes in the progression of diabetic retinopathy

This study suggests that SLC1A5 and RPS21 are involved in DR progression, offering potential therapeutic targets. However, further experimental validation is necessary to confirm their functional roles and clinical relevance.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-12
DOI
https://doi.org/10.3389/fendo.2025.1733368
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
0.00

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article

Transcriptome analysis and RT-qPCR validation of mitophagy-related key genes in the progression of diabetic retinopathy

Liangjie Niu, Jianmin Wang, Yifan Zhang, Huika Xia
Frontiers in Endocrinology
Autophagy in Disease and Therapy
article

Transcriptome analysis and RT-qPCR validation of mitophagy-related key genes in the progression of diabetic retinopathy

Liangjie Niu, Jianmin Wang, Yifan Zhang, Huika Xia
article en

Abstract

This study suggests that SLC1A5 and RPS21 are involved in DR progression, offering potential therapeutic targets. However, further experimental validation is necessary to confirm their functional roles and clinical relevance.

Frontiers in EndocrinologyVol. 16
Hebei Medical University (CN), Second Hospital of Hebei Medical University (CN), Hebei General Hospital (CN)
Natural Science Foundation of Hebei Province, Horizon 2020 Framework Programme
Good health and well-being
Openalex Percentile: Top 90%
Autophagy in Disease and Therapy
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