Fronto‐limbic emotional‐processing markers signal risk of onset rather than risk of recurrence in mood disorders: Evidence from a longitudinal twin study

Dysfunctional fronto-limbic processing of facial emotions indicates increased propensity to develop a mood disorder, but is not associated with increased risk for recurrence of mood episodes. This dissociation suggests that distinct neural mechanisms underlie the first-onset versus the recurrence of mood disorders.

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Publication Details

Journal
Psychiatry and Clinical Neurosciences
Published
2026-01-12
DOI
https://doi.org/10.1111/pcn.70026
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Fronto‐limbic emotional‐processing markers signal risk of onset rather than risk of recurrence in mood disorders: Evidence from a longitudinal twin study

Kamilla Woznica Miskowiak, Anjali Sankar, Julian Macoveanu, Kessing Lv et al.
Psychiatry and Clinical Neurosciences
Bipolar Disorder and Treatment
article

Fronto‐limbic emotional‐processing markers signal risk of onset rather than risk of recurrence in mood disorders: Evidence from a longitudinal twin study

Kamilla Woznica Miskowiak, Anjali Sankar, Julian Macoveanu, Kessing Lv, Hartwig R Siebner, Maj Vinberg, Hanne Lie Kjærstad
article en

Abstract

Dysfunctional fronto-limbic processing of facial emotions indicates increased propensity to develop a mood disorder, but is not associated with increased risk for recurrence of mood episodes. This dissociation suggests that distinct neural mechanisms underlie the first-onset versus the recurrence of mood disorders.

Psychiatry and Clinical Neurosciences
University of Copenhagen (DK), Mental Health Services (DK), Amager Hospital (DK), Frederiksberg Hospital (DK), Hvidovre Hospital (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK), Capital Region of Denmark (DK)
Openalex Percentile: Top 90%
Bipolar Disorder and Treatment
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