Liver metastasis of ovarian granulosa cell tumors: a case report and literature review

This case highlights the potential of ovarian GCT for late recurrence- even decades after primary treatment. A literature review revealed that, to date, only 21 cases of GCT with liver metastasis have been reported, with the interval between the diagnosis of the primary tumor and the development of liver metastasis ranging from 6 to 40 years. Close long-term follow-up is essential to detect recurrence early and optimize patient outcomes.

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Publication Details

Journal
BMC Women s Health
Published
2026-01-12
DOI
https://doi.org/10.1186/s12905-026-04260-1
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Liver metastasis of ovarian granulosa cell tumors: a case report and literature review

Aihua Li, Tingting Jiao, L L Zhao, Xian Zhang et al.
BMC Women s Health
Ovarian cancer diagnosis and treatment
article

Liver metastasis of ovarian granulosa cell tumors: a case report and literature review

Aihua Li, Tingting Jiao, L L Zhao, Xian Zhang, Xiaoping Ma, Yan Zhang, Lili zheng, Jinqiang Yan
article en

Abstract

This case highlights the potential of ovarian GCT for late recurrence- even decades after primary treatment. A literature review revealed that, to date, only 21 cases of GCT with liver metastasis have been reported, with the interval between the diagnosis of the primary tumor and the development of liver metastasis ranging from 6 to 40 years. Close long-term follow-up is essential to detect recurrence early and optimize patient outcomes.

BMC Women s HealthVol. 26(1)
Chinese PLA General Hospital (CN), Liaocheng People's Hospital (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 91%
Ovarian cancer diagnosis and treatment
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