Enantioselective Reduction of Hex-5-en-2-one and 6-Methylhept-5-en-2-one, Catalyzed by Petroselinum crispum Cells

Previously, we studied the enantioselective reduction of prochiral saturated aliphatic ketones, catalyzed by available biocatalysts, leading to the formation of the corresponding secondary S-alcohols. In this study, to investigate the synthetic potential of a biocatalyst based on the Petroselinum crispum culture, we explored the possibility of biocatalytic reduction of prochiral unsaturated aliphatic ketones, exemplified by hex-5-en-2-one and 6-methylhept-5-en-2-one, to the respective (S)-(+)-hex-5-en-2-ol and (S)-(+)-6-methylhept-5-en-2-ol, precursors in the synthesis of biologically active substances used in agriculture and medicine.