Efficacy and Safety of Treatment With Low Doses of Spironolactone in Patients With Primary Aldosteronism: A Retrospective Observational Study in a Tertiary Center
Treatment with low doses of spironolactone, in association with other antihypertensive drugs, is effective in achieving an appropriate blood pressure control in primary aldosteronism, while it improves adherence with lower adverse effects. These findings could help the clinician choose the best therapeutic option for each patient.
Authors
- L. Amar
- Julien Riancho
- Diana Ferrão (ORCID: https://orcid.org/0000-0002-2062-3649)
- Elisa Deflorenne
- Elisa Sconfienza (ORCID: https://orcid.org/0000-0001-9558-6013)
- Mostafa Azizi (ORCID: https://orcid.org/0000-0001-9936-3001)
- Nicole Gebara (ORCID: https://orcid.org/0000-0002-6507-759X)
- Jean-Baptiste de Fréminville
- Aurélien Lorthioir
- Jacopo Burrello
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Hospital de São João (PT)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Hôpital Européen (FR)
- Department of Medical Sciences (BY)
- Paris Cardiovascular Research Center (FR)
Publication Details
- Journal
- Hypertension
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1161/hypertensionaha.125.24881
- Citations
- 1
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 30.73