Predictors of achieving clinical remission in ACPA-positive RA-patients treated with abatacept and methotrexate and methotrexate monotherapy: a post-hoc analysis of the AVERT and AVERT-II trials
Determining which patients achieve clinical remission upon methotrexate or abatacept+methotrexate treatment remains challenging. Disease activity at disease presentation and early DAS response were the only consistent predictors for achieving clinical remission. Genetic, imaging and serology parameters did not improve model performance.
Authors
- S. A. Bergstra
- T.W.J. Huizinga
- A.H.M. van der Helm van Mil
- E. Niemantsverdriet
- M. Verstappen
Institutions
- Leiden University Medical Center (NL)
Publication Details
- Journal
- Seminars in Arthritis and Rheumatism
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1016/j.semarthrit.2026.152917
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00