Periungual Bowen Disease Mimicking a Melanocytic Nevus: A Case Report

Periungual Bowen disease is an uncommon form of squamous cell carcinoma in situ that may mimic benign pigmented lesions, such as melanocytic nevi. We report a case of a 36-year-old man who presented with an irregularly shaped brown macule on the periungual area of the right third finger, with a history of gradual enlargement over 8 years. The patient reported occasional periungual trauma because of nail picking but had no significant medical history. A punch biopsy was performed, and histopathological examination confirmed the diagnosis of Bowen disease. The lesion was completely excised, and no recurrence was observed during follow-up. This case highlights the importance of clinical suspicion and histological evaluation for chronic pigmented periungual lesions that may resemble benign conditions.

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Publication Details

Journal
American Journal of Dermatopathology
Published
2026-01-12
DOI
https://doi.org/10.1097/dad.0000000000003216
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
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article

Periungual Bowen Disease Mimicking a Melanocytic Nevus: A Case Report

Sin Sung, Yoon Hwan Lee, Ji Youn Hong
American Journal of Dermatopathology
Nonmelanoma Skin Cancer Studies
article

Periungual Bowen Disease Mimicking a Melanocytic Nevus: A Case Report

Sin Sung, Yoon Hwan Lee, Ji Youn Hong
article en

Abstract

Periungual Bowen disease is an uncommon form of squamous cell carcinoma in situ that may mimic benign pigmented lesions, such as melanocytic nevi. We report a case of a 36-year-old man who presented with an irregularly shaped brown macule on the periungual area of the right third finger, with a history of gradual enlargement over 8 years. The patient reported occasional periungual trauma because of nail picking but had no significant medical history. A punch biopsy was performed, and histopathological examination confirmed the diagnosis of Bowen disease. The lesion was completely excised, and no recurrence was observed during follow-up. This case highlights the importance of clinical suspicion and histological evaluation for chronic pigmented periungual lesions that may resemble benign conditions.

American Journal of DermatopathologyVol. 48(3)
Chung-Ang University Hospital (KR), Chung-Ang University (KR)
Good health and well-being
Openalex Percentile: Top 90%
Nonmelanoma Skin Cancer Studies
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Periungual Bowen Disease Mimicking a Melanocytic Nevus: A Case Report — Sin Sung, Yoon Hwan Lee, et al. · American Journal of Dermatopathology (2026) | TGRS Research Map | TGRS