CIT kinase phosphorylation as significant regulatory node for cellular checkpoints
These findings suggest that CIT_S440 functions as a promising therapeutic target, and the phosphosite-centric regulatory network derived in this study could serve as a platform to evaluate its phosphosite-specific therapeutic interventions.
Authors
- Rajesh Raju (ORCID: https://orcid.org/0000-0003-2319-121X)
- Sowmya Soman (ORCID: https://orcid.org/0009-0003-1452-2627)
- Levin John
- Athira Perunelly Gopalakrishnan
- Althaf Mahin (ORCID: https://orcid.org/0009-0007-6017-4415)
- Prathik Basthikoppa Shivamurthy
- Fathimathul Lubaba
- Jaytha Thomas
- Suhail Subair (ORCID: https://orcid.org/0009-0005-6643-2353)
- Mukhtar Ahmed (ORCID: https://orcid.org/0000-0001-7392-6312)
Institutions
- Yenepoya University (IN)
- King Saud University (SA)
- MRC Centre for Regenerative Medicine (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Frontiers in Bioinformatics
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fbinf.2025.1734030
- Primary Topic
- Microtubule and mitosis dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00