Serum cystatin C as a biomarker for diabetic retinopathy and its role in diabetic retinopathy-diabetic kidney disease comorbidity
The renal dysfunction biomarkers CysC and eGFR<sub>CysC</sub> were identified as key biomarkers for NPDR, while eGFR<sub>rediff</sub> and UACR were predictive for PDR. MR analyses confirmed CysC as a strong risk factor for DR susceptibility, particularly in the early stages.
Authors
- Yiyun Zeng (ORCID: https://orcid.org/0009-0007-6290-2957)
- W Yuan
- Xinming Gu
- H T Wu
- Yang Yang
- Xiaosi Chen
- Linghui Pi
- Xinyuan Zhang (ORCID: https://orcid.org/0000-0002-3372-0798)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Jingdong (China) (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1186/s12967-025-07552-6
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00