Independent and Joint Associations of Circadian Rhythm Patterns and Physical Activity Levels With Venous Thromboembolism: A Large-Scale Cohort Study Using Accelerometry Measurements

This large-scale cohort study demonstrates that disrupted circadian rhythms and low PA are independently and jointly associated with elevated VTE risk. These findings suggest that circadian and activity monitoring, for example, via wearable devices, may have potential utility in future VTE risk assessment particularly among high-risk populations.