Risk factors for hemodynamically significant patent ductus arteriosus and ibuprofen treatment failure in premature twins: a retrospective case-control study
In preterm twins ≤34 weeks, sIUGR is an IRF for hsPDA. In addition, MCDA and PROMs > 18 h are IRFs for ibuprofen treatment failure. Meanwhile, elevated levels of NT-proBNP and Hs-cTn may play a role in the development of hsPDA in preterm infants with sIUGR.
Authors
- Wang Pa
- Y. Wu
- Hezhi Li (ORCID: https://orcid.org/0000-0002-8054-9284)
- Bo Gao (ORCID: https://orcid.org/0000-0003-3070-2962)
- Yue Du
- Yixue Zhao
- Guijun Chen
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Key Laboratory of Guangdong Province (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fcvm.2025.1687361
- Primary Topic
- Cardiovascular Conditions and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00