Total outflow facility before and after goniotomy in ex vivo perfusion models for aqueous humor dynamics: effect of periocular tissue
This study demonstrates the influence of distal outflow pathways on C<sub>tot</sub> with intact TM and after goniotomy. Thus, tissue preparation is a potential confounder in <i>ex vivo</i> AHO perfusion setups and may contribute to the different effect sizes of TM bypass surgery between <i>ex vivo</i> and <i>in vivo</i> studies.
Authors
- Martin Kallab (ORCID: https://orcid.org/0000-0002-7452-6334)
- Alex S. Huang (ORCID: https://orcid.org/0000-0001-9024-9608)
- Sarah Hinterberger
- Parsa Hassani Shariat Panahi (ORCID: https://orcid.org/0009-0005-2912-3754)
- Matthias Bolz
- Silvia Kaltenboeck
Institutions
- Johannes Kepler University of Linz (AT)
- University of San Diego (US)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fmed.2025.1705023
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Glaucoma Research Foundation
- Research to Prevent Blindness
- Austrian Science Fund
- National Institutes of Health
- University of California, San Diego