Mendelian randomization study of GLP-1R effects on ovarian cancer subtypes mediated by metabolic factors

The protective effect of GLP-1R agonists on ovarian cancer, especially ENOC, needs further validation in large-scale and well-conducted clinical trials.

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Publication Details

Journal
Communications Medicine
Published
2026-01-12
DOI
https://doi.org/10.1038/s43856-026-01379-y
Primary Topic
Metabolism, Diabetes, and Cancer
Type
article
Field-Weighted Citation Impact
0.00

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article

Mendelian randomization study of GLP-1R effects on ovarian cancer subtypes mediated by metabolic factors

Qiuhong Gong, Yuhong Chen, Jieli Lu, Yufang Bi et al.
Communications Medicine
Metabolism, Diabetes, and Cancer
article

Mendelian randomization study of GLP-1R effects on ovarian cancer subtypes mediated by metabolic factors

Qiuhong Gong, Yuhong Chen, Jieli Lu, Yufang Bi, Limin Wang, Qian Yang, Shuangyuan Wang, Min Xu, Hong Lin, Yu Xu, Mian Li, Zhihe Chen, Jie Zheng, Tiange Wang, Zhiyun Zhao, Guang Ning
article en

Abstract

The protective effect of GLP-1R agonists on ovarian cancer, especially ENOC, needs further validation in large-scale and well-conducted clinical trials.

Communications MedicineVol. 6(1)
Shanghai Jiao Tong University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Ruijin Hospital (CN), University of Bristol (GB), National Center for Chronic and Noncommunicable Disease Control and Prevention (CN), MRC Epidemiology Unit (GB)
National Natural Science Foundation of China, Shanghai Municipal Education Commission, National Science and Technology Major Project, National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 91%
Metabolism, Diabetes, and Cancer
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