VEGF-inhibitor switch trial in poor-responsive neovascular age-related macular degeneration: assessing brolucizumab vs. faricimab: VISTA study

In poor-responsive nAMD, switching to BRZ or FAR under a TAE regimen without upload achieved stable vision, sustained CST reduction, and comparable treatment burden over one year. FAR showed greater fvPED regression and a slight functional trend, while BRZ achieved faster fluid resolution with fewer injections.

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Publication Details

Journal
Graefe s Archive for Clinical and Experimental Ophthalmology
Published
2026-01-12
DOI
https://doi.org/10.1007/s00417-025-07091-2
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

VEGF-inhibitor switch trial in poor-responsive neovascular age-related macular degeneration: assessing brolucizumab vs. faricimab: VISTA study

Armin Wolf, Efstathios Vounotrypidis, Adnan Kilani, Vasiliki Moysidi et al.
Graefe s Archive for Clinical and Experimental Ophthalmology
Retinal Diseases and Treatments
article

VEGF-inhibitor switch trial in poor-responsive neovascular age-related macular degeneration: assessing brolucizumab vs. faricimab: VISTA study

Armin Wolf, Efstathios Vounotrypidis, Adnan Kilani, Vasiliki Moysidi, Abdelrahman Assaf, Denise Vogt
article en

Abstract

In poor-responsive nAMD, switching to BRZ or FAR under a TAE regimen without upload achieved stable vision, sustained CST reduction, and comparable treatment burden over one year. FAR showed greater fvPED regression and a slight functional trend, while BRZ achieved faster fluid resolution with fewer injections.

Graefe s Archive for Clinical and Experimental Ophthalmology
University Hospital Ulm (DE)
No poverty
Openalex Percentile: Top 90%
Retinal Diseases and Treatments
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