Integrative single cell <scp>RNA</scp> ‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

The findings of this study offer a groundwork in tailoring novel targets and therapies for FAI and hip OA patients.

Authors

Institutions

Publication Details

Journal
Arthritis & Rheumatology
Published
2026-01-12
DOI
https://doi.org/10.1002/art.70033
Primary Topic
Hip disorders and treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Integrative single cell RNA ‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Eloise Fadial, Victoria L. Hansen, Alexis Klee, Eliya Tazreena Tashbib et al.
Arthritis & Rheumatology
Hip disorders and treatments
article

Integrative single cell RNA ‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Eloise Fadial, Victoria L. Hansen, Alexis Klee, Eliya Tazreena Tashbib, John Reuter, Brian Giordano, Mina Botros, Chia‐Lung Wu, Gulzada Kulzhanova, Benjamin F. Ricciardi
article en

Abstract

The findings of this study offer a groundwork in tailoring novel targets and therapies for FAI and hip OA patients.

Arthritis & Rheumatology
University of Rochester Medical Center (US), Children's Hospital of Richmond at VCU (US), University of Rochester (US)
Openalex Percentile: Top 91%
Hip disorders and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.