24-hour NIHSS may be a reliable surrogate for 90-day mRS after mechanical thrombectomy—a prospective study in anterior and posterior circulation infarctions

The 24-h NIHSS is a reliable early surrogate for 90-day functional recovery post-MT in both ACI and PCI, outperforming both baseline NIHSS and <i>Δ</i>-NIHSS. The non-linear relationship between 24-h NIHSS and functional independence highlights that treating it as a continuous variable has limitations, strongly supporting the use of this pragmatic cutoff rather than treating the scale as a simple continuous linear predictor.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-12
DOI
https://doi.org/10.3389/fneur.2025.1698534
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

24-hour NIHSS may be a reliable surrogate for 90-day mRS after mechanical thrombectomy—a prospective study in anterior and posterior circulation infarctions

Juan Luo, Guoliang Zhu, Quan Liu, Jie Yang et al.
Frontiers in Neurology
Acute Ischemic Stroke Management
article

24-hour NIHSS may be a reliable surrogate for 90-day mRS after mechanical thrombectomy—a prospective study in anterior and posterior circulation infarctions

Juan Luo, Guoliang Zhu, Quan Liu, Jie Yang, Qing He
article en

Abstract

The 24-h NIHSS is a reliable early surrogate for 90-day functional recovery post-MT in both ACI and PCI, outperforming both baseline NIHSS and <i>Δ</i>-NIHSS. The non-linear relationship between 24-h NIHSS and functional independence highlights that treating it as a continuous variable has limitations, strongly supporting the use of this pragmatic cutoff rather than treating the scale as a simple continuous linear predictor.

Frontiers in NeurologyVol. 16
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN), Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN), First Affiliated Hospital of Chengdu Medical College (CN), Chengdu Second People's Hospital (CN)
Openalex Percentile: Top 90%
Acute Ischemic Stroke Management
DOIOpen Access PDFOpenAlex
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24-hour NIHSS may be a reliable surrogate for 90-day mRS after mechanical thrombectomy—a prospective study in anterior and posterior circulation infarctions — Juan Luo, Guoliang Zhu, et al. · Frontiers in Neurology (2026) | TGRS Research Map | TGRS