Elevated maternal pre-transfer serum lipid peroxidation is associated with implantation failure and early pregnancy loss
Elevated maternal lipid peroxidation is independently associated with RIF. In patients without RIF, it is similarly associated with implantation failure and early pregnancy loss. The endometrium appears particularly sensitive to this peroxidation, which may impair receptivity and decidualization. These support further investigation of redox-modulating strategies in ART.
Authors
- Junxiang Ren (ORCID: https://orcid.org/0000-0002-0879-2685)
- Tao Ni (ORCID: https://orcid.org/0000-0001-7268-0306)
- Junhao Yan (ORCID: https://orcid.org/0000-0002-7110-8698)
- Jia Yuan (ORCID: https://orcid.org/0000-0002-4807-8646)
- X. Liu (ORCID: https://orcid.org/0000-0002-2368-7680)
- Zhangwei Jia
- W J Zhou
- Chenxi Jin
- Qian Zhang
Institutions
- Shandong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shandong Academy of Chinese Medicine (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1186/s12916-026-04618-0
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00