Association of Organ Preservation Methods With Von Willebrand Factor Upregulation in Microvascular Endothelial Cells Posttransplantation: Ex Vivo Lung Perfusion and Static Cold Storage
Increased VWF expression in microvascular endothelial cells under SCS may contribute to transplant-associated thrombogenicity. Decreasing VWF expression through ex vivo normothermic perfusion could significantly mitigate the risk of thrombogenic complications, a major complication of organ transplantation.
Authors
- Catherine J. Stewart (ORCID: https://orcid.org/0000-0001-9231-2922)
- Sanaz Hatami (ORCID: https://orcid.org/0000-0002-6792-6620)
- Sayed Himmat (ORCID: https://orcid.org/0000-0002-1586-996X)
- Nader S. Aboelnazar
- Nicholas M. Fialka (ORCID: https://orcid.org/0000-0002-7277-6188)
- Nadia Jahroudi (ORCID: https://orcid.org/0000-0002-6008-7975)
- Max Buchko (ORCID: https://orcid.org/0000-0002-4396-1229)
- Darren H. Freed
- Parnian Alavi
- Jayan Nagendran
- Keir A. Forgie
Institutions
- University of Alberta (CA)
Publication Details
- Journal
- Transplantation Direct
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1097/txd.0000000000001898
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Alberta
- Natural Sciences and Engineering Research Council of Canada