Association of <i>FADS2</i> polymorphism rs174538 with fatty acid metabolism and disease severity in Japanese patients with Crohn’s disease
The rs174538 mutation alters the fatty acid profile through strong linkage to the <i>FADS1</i> gene. In <i>wild</i>-type individuals, rd.d6di was positively correlated with CDAI, suggesting predictive utility of disease severity.
Authors
- Shigeo Koido (ORCID: https://orcid.org/0000-0003-0397-4348)
- Shizuka Suzuki (ORCID: https://orcid.org/0009-0009-0480-9409)
- Yutaro Motoi
- Zensho Ito (ORCID: https://orcid.org/0000-0002-8069-8984)
- Yuichiro Ohtaki
- H. Matsuzawa
- Takahiro Kubota (ORCID: https://orcid.org/0000-0001-8135-7033)
- Kan Uchiyama
- Kana Kojima
- Tatsuya Nakada
- Kota Murohashi
- Yuko Iwashita
- Toshifumi Ohkusa
Institutions
- Niigata University of Pharmacy and Medical and Life Sciences (JP)
- Jikei University School of Medicine (JP)
- Juntendo University (JP)
- Jikei University Kashiwa hospital (JP)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3748/wjg.v32.i2.112132
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00