False positives in transfusion-transmitted infection proficiency testing due to matrix effects in external quality assessment samples: lessons for clinical laboratories
Matrix interference in proficiency testing, although rare, can compromise interpretation. Reflex testing, structured root cause analysis, robust standard operating procedures, staff training, and attention to sample commutability are essential to strengthen quality assurance.
Authors
- Sadhana Mangwana
- Anil Handoo (ORCID: https://orcid.org/0000-0002-1075-1268)
- Amena Ebadur Rahman (ORCID: https://orcid.org/0000-0002-4571-802X)
- Rasika Setia (ORCID: https://orcid.org/0000-0002-1187-6871)
- Gajendra Nath Gupta
- Mitu Dogra
- Deepti Sachan
Institutions
- ActionAid (US)
- Tamil Nadu Dr. M.G.R. Medical University (IN)
- Max Super Speciality Hospital (IN)
- BLK Super Speciality Hospital (IN)
- Federal State Budgetary Institution "Center for Expertise and Quality Control of Medical Care" (RU)
Publication Details
- Journal
- Laboratory Medicine
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1093/labmed/lmaf090
- Primary Topic
- Clinical Laboratory Practices and Quality Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00