LncRNA DANCR promotes ABL2-mediated metastasis via decoying of miR-125a-5p in high-risk neuroblastoma
In summary, our findings delineate the DANCR/miR-125a-5p/ABL2/cofilin axis as a critical regulator of cytoskeletal dynamics in neuroblastoma metastasis, offering novel insights for the diagnosis and therapeutic targeting of high-risk neuroblastoma.
Authors
- Daowei Wang (ORCID: https://orcid.org/0000-0001-8380-6509)
- Mingyou Gao (ORCID: https://orcid.org/0000-0001-8931-6164)
- Yan Guo (ORCID: https://orcid.org/0009-0000-1017-2453)
- J. Zhang (ORCID: https://orcid.org/0000-0002-5081-7698)
- Yuanyuan Liu
- Lin Lu
- Yun Liu
- Junling Li
- Yuren Xia
- Jie Li
- Fang Cao
- Qiang Zhao
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Second Hospital of Tianjin Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fonc.2025.1721248
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Tianjin City
- Tianjin Medical University
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences