Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

For almost all markers in CSF, a significant effect of age alone on the markers or a significant effect of sex and age on the markers could be detected. Our study underscores the importance of age- and sex-adjusted reference values for the interpretation of CSF markers in clinical practice.

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Publication Details

Journal
Annals of Clinical and Translational Neurology
Published
2026-01-12
DOI
https://doi.org/10.1002/acn3.70307
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Simon Faissner, Ralf Gold, Isabel‐Sophie Hafer, Aiden Haghikia
Annals of Clinical and Translational Neurology
Cerebrospinal fluid and hydrocephalus
article

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Simon Faissner, Ralf Gold, Isabel‐Sophie Hafer, Aiden Haghikia
article en

Abstract

For almost all markers in CSF, a significant effect of age alone on the markers or a significant effect of sex and age on the markers could be detected. Our study underscores the importance of age- and sex-adjusted reference values for the interpretation of CSF markers in clinical practice.

Annals of Clinical and Translational Neurology
Medizinische Hochschule Hannover (DE), St. Josef-Hospital (DE)
Openalex Percentile: Top 91%
Cerebrospinal fluid and hydrocephalus
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