Fluconazole resistance among Candida species with special emphasis on ERG11 gene mutations among Candida tropicalis

The study concludes that antifungal susceptibility testing (AST) using Vitek-2 is a preferred method in the laboratory for identifying <i>Candida</i> species and performing susceptibility testing due to its ease of use and cost-effectiveness. Disc diffusion can be utilized in resource-limited settings to guide treatment, while PCR and newer molecular methods offer valuable opportunities for researching different mechanisms and mutations responsible for fluconazole resistance, a widely used antifungal for treatment and prevention.

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Publication Details

Journal
Frontiers in Fungal Biology
Published
2026-01-12
DOI
https://doi.org/10.3389/ffunb.2025.1695271
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00

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article

Fluconazole resistance among Candida species with special emphasis on ERG11 gene mutations among Candida tropicalis

Vidyavathi B. Chitharagi, Yogeesh D. Maheshwarappa, S M S, Morubagal Raghavendra Rao et al.
Frontiers in Fungal Biology
Antifungal resistance and susceptibility
article

Fluconazole resistance among Candida species with special emphasis on ERG11 gene mutations among Candida tropicalis

Vidyavathi B. Chitharagi, Yogeesh D. Maheshwarappa, S M S, Morubagal Raghavendra Rao, Mahadevaiah Neelambike Sumana, Gowthami S.
article en

Abstract

The study concludes that antifungal susceptibility testing (AST) using Vitek-2 is a preferred method in the laboratory for identifying <i>Candida</i> species and performing susceptibility testing due to its ease of use and cost-effectiveness. Disc diffusion can be utilized in resource-limited settings to guide treatment, while PCR and newer molecular methods offer valuable opportunities for researching different mechanisms and mutations responsible for fluconazole resistance, a widely used antifungal for treatment and prevention.

Frontiers in Fungal BiologyVol. 6
JSS Academy of Higher Education and Research (IN)
JSS Academy of Higher Education and Research
Openalex Percentile: Top 89%
Antifungal resistance and susceptibility
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