Fluconazole resistance among Candida species with special emphasis on ERG11 gene mutations among Candida tropicalis
The study concludes that antifungal susceptibility testing (AST) using Vitek-2 is a preferred method in the laboratory for identifying <i>Candida</i> species and performing susceptibility testing due to its ease of use and cost-effectiveness. Disc diffusion can be utilized in resource-limited settings to guide treatment, while PCR and newer molecular methods offer valuable opportunities for researching different mechanisms and mutations responsible for fluconazole resistance, a widely used antifungal for treatment and prevention.
Authors
- Vidyavathi B. Chitharagi (ORCID: https://orcid.org/0000-0003-2961-1799)
- Yogeesh D. Maheshwarappa
- S M S
- Morubagal Raghavendra Rao
- Mahadevaiah Neelambike Sumana
- Gowthami S.
Institutions
- JSS Academy of Higher Education and Research (IN)
Publication Details
- Journal
- Frontiers in Fungal Biology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/ffunb.2025.1695271
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- JSS Academy of Higher Education and Research