Molecular markers of pediatric cholesteatoma: A gene expression comparison with adult tissue
Pediatric cholesteatoma has distinct gene expression and pathway enrichment compared to adult disease, involving inflammation and fibrosis. This study highlights the complex inflammatory process seen in pediatric cholesteatoma and suggests molecular markers that could serve as potential therapeutic targets for treatment.
Authors
- Kelly Otsuka (ORCID: https://orcid.org/0000-0001-6559-9438)
- Michael Seipp
- Peter Kfoury (ORCID: https://orcid.org/0000-0002-2885-7108)
- Sarah H. AL Nemer
- Matthew A. Firpo
- Albert H. Park
- Mack Tempero
Institutions
- University of Utah (US)
Publication Details
- Journal
- International Journal of Pediatric Otorhinolaryngology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1016/j.ijporl.2026.112721
- Primary Topic
- Ear Surgery and Otitis Media
- Type
- article
- Field-Weighted Citation Impact
- 0.00