Efficacy of whole-brain radiotherapy with or without simultaneous integrated boost in non-small cell lung cancer with brain metastases: a retrospective analysis
WBRT-SIB provided comparable overall intracranial control to conventional WBRT but achieved superior local tumor control in patients with limited brain metastases (< 8 lesions). These findings support WBRT-SIB as a promising option for selected NSCLC-BM patients, warranting validation in prospective studies.
Authors
- Biyuan Zhang (ORCID: https://orcid.org/0000-0002-4943-3136)
- Lan Wang
- Haiji Wang
- Wen Gao
- Tianhui Guo
- Wenqian Fu
- Meng Zhang
- Qi Wang
- Bingxin Zhao
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fmed.2025.1733289
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00