Targeted analysis of sphingolipids and cytokines in plasma of dairy cows after calving reveals distinct impacts of systemic inflammation, ketosis, and mastitis

In summary, heightened inflammatory response in early post-partum is associated with the strongest systemic effects on SL metabolism, followed by ketosis, while mastitis induced only modest alterations. These findings highlight condition-specific patterns of SL regulation postpartum and suggest potential immunometabolic biomarkers of disease.

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Publication Details

Journal
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Published
2026-01-12
DOI
https://doi.org/10.1186/s40104-025-01325-3
Primary Topic
Animal health and immunology
Type
article
Field-Weighted Citation Impact
0.00

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article

Targeted analysis of sphingolipids and cytokines in plasma of dairy cows after calving reveals distinct impacts of systemic inflammation, ketosis, and mastitis

Blandine Gausserès, Philippe Guerre, Elodie Lassallette, Gilles Foucras et al.
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Animal health and immunology
article

Targeted analysis of sphingolipids and cytokines in plasma of dairy cows after calving reveals distinct impacts of systemic inflammation, ketosis, and mastitis

Blandine Gausserès, Philippe Guerre, Elodie Lassallette, Gilles Foucras, Alix Pierron Baysse
article en

Abstract

In summary, heightened inflammatory response in early post-partum is associated with the strongest systemic effects on SL metabolism, followed by ketosis, while mastitis induced only modest alterations. These findings highlight condition-specific patterns of SL regulation postpartum and suggest potential immunometabolic biomarkers of disease.

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnologyVol. 17(1)
École Nationale Vétérinaire de Toulouse (FR), Université Fédérale de Toulouse Midi-Pyrénées (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Centre Régional d’Innovation et de Transferts Technologiques des Industries du Bois (FR), Interactions hôtes-agents pathogènes (FR)
APIS-GENE
Openalex Percentile: Top 90%
Animal health and immunology
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