Clival metastasis of hepatocellular carcinoma: a case report of a rare skull-base malignancy

In the case of a suspected clivus metastasis of unknown origin, it is reasonable to take tumor markers. This increases the likelihood of an appropriate diagnosis and avoids unnecessary and risky surgery. If all tests are inconclusive, a biopsy of the lesion is the diagnostic gold standard. The treatment of metastatic disease in the clivus (in our case a hepatocellular carcinoma) remains palliative.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-12
DOI
https://doi.org/10.3389/fonc.2025.1567187
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Clival metastasis of hepatocellular carcinoma: a case report of a rare skull-base malignancy

Matic Bošnjak, Jure Urbančič, Tomislav Felbabić, Domen Vozel et al.
Frontiers in Oncology
Brain Metastases and Treatment
article

Clival metastasis of hepatocellular carcinoma: a case report of a rare skull-base malignancy

Matic Bošnjak, Jure Urbančič, Tomislav Felbabić, Domen Vozel, Roman Bošnjak
article en

Abstract

In the case of a suspected clivus metastasis of unknown origin, it is reasonable to take tumor markers. This increases the likelihood of an appropriate diagnosis and avoids unnecessary and risky surgery. If all tests are inconclusive, a biopsy of the lesion is the diagnostic gold standard. The treatment of metastatic disease in the clivus (in our case a hepatocellular carcinoma) remains palliative.

Frontiers in OncologyVol. 15
University of Ljubljana (SI), Ljubljana University Medical Centre (SI)
Good health and well-being
Openalex Percentile: Top 91%
Brain Metastases and Treatment
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