Lipid and immune dysregulation and risk of metabolic disorders after HCV clearance in HIV/HCV-coinfected participants with cACLD: a retrospective study
Pre-treatment lipid and immune dysregulation was associated with post-SVR metabolic events in HIV/HCV-coinfected participants, suggesting that HCV may leave a lasting metabolic imprint that contributes to adverse outcomes after viral clearance.
Authors
- Rubén Martín‐Escolano (ORCID: https://orcid.org/0000-0002-6262-9344)
- Juan Berenguer (ORCID: https://orcid.org/0000-0001-8541-8200)
- Belén Requena (ORCID: https://orcid.org/0000-0003-4710-0685)
- Coral Barbas
- María Ángeles Jiménez-Sousa
- Cristina Díez
- Ana Virseda-Berdices
- Carolina Gonzalez-Riano
- Salvador Resino
- Amanda Fernández-Rodríguez
- Victor Hontañon
Institutions
- Universidad San Pablo CEU (ES)
- Hospital Universitario La Paz (ES)
- Instituto de Salud Carlos III (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Centro Nacional de Microbiologia (ES)
- Hospital La Paz Institute for Health Research (ES)
- Centro de Investigación Biomédica en Red (ES)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1674837
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto de Salud Carlos III