Transforming wearable data into personal health insights using large language model agents

Deriving personalized insights from popular wearable trackers requires complex numerical reasoning that challenges standard LLMs, necessitating tool-based approaches like code generation. Large language model (LLM) agents present a promising yet largely untapped solution for this analysis at scale. We introduce the Personal Health Insights Agent (PHIA), a system leveraging multistep reasoning with code generation and information retrieval to analyze and interpret behavioral health data. To test its capabilities, we create and share two benchmark datasets with over 4000 health insights questions. A 650-hour human expert evaluation shows that PHIA significantly outperforms a strong code generation baseline, achieving 84% accuracy on objective, numerical questions and, for open-ended ones, earning 83% favorable ratings while being twice as likely to achieve the highest quality rating. This work can advance behavioral health by empowering individuals to understand their data, enabling a new era of accessible, personalized, and data-driven wellness for the wider population.

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Publication Details

Journal
Nature Communications
Published
2026-01-12
DOI
https://doi.org/10.1038/s41467-025-67922-y
Citations
3
Primary Topic
Digital Mental Health Interventions
Type
article
Field-Weighted Citation Impact
120.31
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article

Transforming wearable data into personal health insights using large language model agents

Naghmeh Rezaei, Hao-Wei Su, Akshay Paruchuri, Nova Hammerquist et al.
3 citations
Nature Communications
Digital Mental Health Interventions
120.31
article

Transforming wearable data into personal health insights using large language model agents

Naghmeh Rezaei, Hao-Wei Su, Akshay Paruchuri, Nova Hammerquist, Erik Schenck, Yi Liu, Qian He, Javier Perez, Jiening Zhan, Mark Malhotra, Jake Sunshine, Shyam Tailor, Tim Althoff, Mike A. Merrill, Yun Liu, Daniel McDuff, Kumar Ayush, Cory Y. McLean, Geza Kovacs
article en
3 citations

Abstract

Deriving personalized insights from popular wearable trackers requires complex numerical reasoning that challenges standard LLMs, necessitating tool-based approaches like code generation. Large language model (LLM) agents present a promising yet largely untapped solution for this analysis at scale. We introduce the Personal Health Insights Agent (PHIA), a system leveraging multistep reasoning with code generation and information retrieval to analyze and interpret behavioral health data. To test its capabilities, we create and share two benchmark datasets with over 4000 health insights questions. A 650-hour human expert evaluation shows that PHIA significantly outperforms a strong code generation baseline, achieving 84% accuracy on objective, numerical questions and, for open-ended ones, earning 83% favorable ratings while being twice as likely to achieve the highest quality rating. This work can advance behavioral health by empowering individuals to understand their data, enabling a new era of accessible, personalized, and data-driven wellness for the wider population.

Nature CommunicationsVol. 17(1)
Google (United States) (US)
Openalex Percentile: Top 0%
Digital Mental Health Interventions
120.31
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Transforming wearable data into personal health insights using large language model agents — Naghmeh Rezaei, Hao-Wei Su, et al. · Nature Communications (2026) | TGRS Research Map | TGRS