Rewiring the aging brain: exergaming modulates brain complexity in older adults

Resting-state changes indicated a shift toward a younger brain profile, characterized by a transition from age-related increases in local processing to enhanced distributed processing, which may potentially mitigate the rise in neural modularity associated with aging. During gameplay, brain signal complexity decreased in week 2, followed by a modest change by week 4, consistent with the framework in which complexity initially streamlines and then adjusts toward a task-specific optimum. These findings suggest that exergaming can beneficially modulate brain complexity in older adults, offering the potential to reduce age-related neural decline and support healthy brain aging.

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Publication Details

Journal
Frontiers in Aging Neuroscience
Published
2026-01-12
DOI
https://doi.org/10.3389/fnagi.2025.1748274
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
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article

Rewiring the aging brain: exergaming modulates brain complexity in older adults

Jochen Baumeister, Daghan Piskin, Helen Müller, Beatrix Vereijken et al.
Frontiers in Aging Neuroscience
Functional Brain Connectivity Studies
article

Rewiring the aging brain: exergaming modulates brain complexity in older adults

Jochen Baumeister, Daghan Piskin, Helen Müller, Beatrix Vereijken, Nina Skjæret-Maroni
article en

Abstract

Resting-state changes indicated a shift toward a younger brain profile, characterized by a transition from age-related increases in local processing to enhanced distributed processing, which may potentially mitigate the rise in neural modularity associated with aging. During gameplay, brain signal complexity decreased in week 2, followed by a modest change by week 4, consistent with the framework in which complexity initially streamlines and then adjusts toward a task-specific optimum. These findings suggest that exergaming can beneficially modulate brain complexity in older adults, offering the potential to reduce age-related neural decline and support healthy brain aging.

Frontiers in Aging NeuroscienceVol. 17
Norwegian University of Science and Technology (NO), Paderborn University (DE)
Openalex Percentile: Top 91%
Functional Brain Connectivity Studies
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