Synthesis of Substituted Potassium 3-(Thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate Derivatives as New Low-Toxicity Sources of Potassium for Agricultural Crops

This paper describes the synthesis and investigation of new substituted potassium 3-(thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate derivatives which can be used in agriculture and have minimal acute toxicity. The obtained substances were characterized by FTIR spectroscopy, NMR spectroscopy, and elemental analysis. Quantitative evaluation of the cytotoxic effect of the developed compounds was identified, and it was determined the seeds germination rate, morpho- and mass-metric characteristics. The results showed that several synthesized compounds demonstrate a high level of biological activity with a low level of acute toxicity. Thus, this indicates the perspectives of further research on this class of compounds.

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Publication Details

Journal
Russian Journal of General Chemistry
Published
2025-12-01
DOI
https://doi.org/10.1134/s1070363225606696
Primary Topic
Synthesis and biological activity
Type
article
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article

Synthesis of Substituted Potassium 3-(Thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate Derivatives as New Low-Toxicity Sources of Potassium for Agricultural Crops

Nailia R. Iamalova, I. A. Gorbunova, Alexander S. Timin, Р. Р. Махмудов et al.
Russian Journal of General Chemistry
Synthesis and biological activity
article

Synthesis of Substituted Potassium 3-(Thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate Derivatives as New Low-Toxicity Sources of Potassium for Agricultural Crops

Nailia R. Iamalova, I. A. Gorbunova, Alexander S. Timin, Р. Р. Махмудов, Vladislava A. Rusakova, Anna Zhuravleva, Sergei A. Shipilovskikh, Natalya A. Nosova, Anastasiya V. Penkova, Gayane G. Panova
article en

Abstract

This paper describes the synthesis and investigation of new substituted potassium 3-(thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate derivatives which can be used in agriculture and have minimal acute toxicity. The obtained substances were characterized by FTIR spectroscopy, NMR spectroscopy, and elemental analysis. Quantitative evaluation of the cytotoxic effect of the developed compounds was identified, and it was determined the seeds germination rate, morpho- and mass-metric characteristics. The results showed that several synthesized compounds demonstrate a high level of biological activity with a low level of acute toxicity. Thus, this indicates the perspectives of further research on this class of compounds.

Russian Journal of General ChemistryVol. 95(12)
Perm State University (RU), St Petersburg University (RU), Peter the Great St. Petersburg Polytechnic University (RU), Agrophysical Research Institute (RU)
Zero hunger
Openalex Percentile: Top 32%
Synthesis and biological activity
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