Death by Neurologic Criteria in Neonates Undergoing Extracorporeal Membrane Oxygenation: Extracorporeal Life Support Organization Registry Study, 2010–2023

DNC is rarely diagnosed in neonatal ECMO cases. Both pre-ECMO and on-ECMO factors associated with DNC included pre-ECMO cardiac arrest, severe metabolic acidosis, and cannulation type. These findings underscore the importance of optimizing pre-ECMO and on-ECMO management and may indicate certain modifiable risk factors such as optimization of cardiopulmonary resuscitation and hyperoxia. Future research should explore preventive strategies and interventions to mitigate the risk of DNC in neonates receiving ECMO.

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Publication Details

Journal
Pediatric Critical Care Medicine
Published
2026-01-12
DOI
https://doi.org/10.1097/pcc.0000000000003891
Citations
1
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
21.28
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article

Death by Neurologic Criteria in Neonates Undergoing Extracorporeal Membrane Oxygenation: Extracorporeal Life Support Organization Registry Study, 2010–2023

A. Guerguerian, A. Gavotto, Susan V. Lipton, A. Hoskote et al.
1 citations
Pediatric Critical Care Medicine
Mechanical Circulatory Support Devices
21.28
article

Death by Neurologic Criteria in Neonates Undergoing Extracorporeal Membrane Oxygenation: Extracorporeal Life Support Organization Registry Study, 2010–2023

A. Guerguerian, A. Gavotto, Susan V. Lipton, A. Hoskote, Lakshmi Raman, Sung-Min Cho, Angelo Polito, Nicolas Joram, Akram M. Zaaqoq, Roberto Lorusso
article en
1 citations

Abstract

DNC is rarely diagnosed in neonatal ECMO cases. Both pre-ECMO and on-ECMO factors associated with DNC included pre-ECMO cardiac arrest, severe metabolic acidosis, and cannulation type. These findings underscore the importance of optimizing pre-ECMO and on-ECMO management and may indicate certain modifiable risk factors such as optimization of cardiopulmonary resuscitation and hyperoxia. Future research should explore preventive strategies and interventions to mitigate the risk of DNC in neonates receiving ECMO.

Pediatric Critical Care MedicineVol. 27(3)
University of Geneva (CH), Boston Children's Hospital (US), Centre National de la Recherche Scientifique (FR), Johns Hopkins University (US), Inserm (FR), University of Toronto (CA), Université de Montpellier (FR), Johns Hopkins Medicine (US), Maastricht University Medical Centre (NL), Great Ormond Street Hospital for Children NHS Foundation Trust (GB), Hospital for Sick Children (CA), University Hospital of Geneva (CH), Laboratoire de Thermique et Energie de Nantes (FR), Bambino Gesù Children's Hospital (IT), Hôpital Arnaud de Villeneuve (FR), Johns Hopkins Hospital (US), University of Virginia (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 3%
Mechanical Circulatory Support Devices
21.28
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