Potential molecular pathways and therapeutic implications of rapid-acting antidepressants on myelin biology: a scoping review
Myelin regulation may represent a component of RAAD action, indicating that these agents could influence myelin biology. Further research is required to clarify the mechanisms underlying these effects, their potential implications for therapies aimed at preserving or restoring myelin integrity, and potential side effects. Their dose-dependent effects highlight the need for careful consideration of dosing and treatment duration.
Authors
- Jared VanderZwaag (ORCID: https://orcid.org/0000-0002-1546-0304)
- Marie‐Ève Tremblay (ORCID: https://orcid.org/0000-0003-2863-9626)
- Colin J. Murray
- Antonella Campanale
- Antonio Inserra
Institutions
- University of Victoria (CA)
- University of Chieti-Pescara (IT)
- Universidade do Sul de Santa Catarina (BR)
- McGill University (CA)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fnins.2025.1690318
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00