Raised alpha fetoprotein in cirrhotic liver with colorectal liver metastasis mimicking hepatocellular carcinoma: case report and review of literature
AFP-producing colorectal adenocarcinoma with liver metastases can masquerade as HCC, particularly in patients with underlying liver disease. This case underscores the need for histological confirmation of atypical hepatic lesions to avoid misdiagnosis. Awareness of this rare entity and careful clinical reasoning are crucial to guide appropriate management and highlight pitfalls in diagnostic practice.
Authors
- Samah Mansour
- Aboje Adugba
- Abdallah Al Farai
- Kareem Al Rezk
- Dominic Obotu Ayegba
- Rawan AlMallah
Institutions
- Sultan Qaboos University Hospital (OM)
- Sultan Qaboos University (OM)
Publication Details
- Journal
- Diagnosis
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1515/dx-2025-0143
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00