Serum osmolarity as a predictor of mortality in ICU COVID-19 patients: a retrospective analysis
Lower admission serum osmolarity and hyponatremia were independently associated with increased in-hospital mortality in critically ill COVID-19 patients. Although Na slightly outperformed calculated osmolarity, the latter remains a practical, integrative prognostic tool for early risk stratification. Prospective studies should evaluate whether timely correction of hypo-osmolar or hyponatremic states improves outcomes.
Authors
- özgür dikme
- Taner Akkoç (ORCID: https://orcid.org/0000-0002-2196-3266)
- Mehmet Toptaş (ORCID: https://orcid.org/0000-0002-3118-8793)
- Abdurrahman Tünay (ORCID: https://orcid.org/0000-0001-7118-9312)
- Mensure Yilmaz Cakirgoz
- Özlem Dikme
Institutions
- Izmir University (TR)
- Fatih University Medical Faculty Hospital (TR)
- Türk Anesteziyoloji ve Reanimasyon Derneği (TR)
- Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi (TR)
Publication Details
- Journal
- PeerJ
- Published
- 2026-01-12
- DOI
- https://doi.org/10.7717/peerj.20590
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00