First‐Year <scp>IgG</scp> Dynamics in <scp>IgG4</scp> ‐Related Disease: A Critical Window for Predicting Long‐Term Outcomes
Baseline IgG elevation marks more severe IgG4-RD phenotypes. The first treatment year achieving IgG normalization represents a critical prognostic biomarker. Failure to normalize IgG within 12 months markedly increases relapse risk. Longitudinal IgG monitoring supports risk stratification and treatment optimization.
Authors
- Boyuan Sun
- Nianyi Zhang
- Jingya Zhou (ORCID: https://orcid.org/0000-0003-4698-567X)
- X X He
- Jie Meng
- Yunyun Fei
- Yuxue Nie
- Jialei Zhang
- Xinli Yang
- Jingna Li
- Mengtao Li
- Yu Peng
- Wen Zhang
- Linyi Peng
- Yifei Wang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- National Cancer Center (US)
- Xuzhou Central Hospital (CN)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1002/art.70056
- Primary Topic
- IgG4-Related and Inflammatory Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Peking Union Medical College Hospital
- National Key Research and Development Program of China