Spurious test results as a diagnostic clue – pseudohyponatremia revealing multiple myeloma
This case highlights the importance of artifacts in laboratory measurement, in this case recognizing analytical interferences when discordant hyponatremia is found. Confirmatory testing by direct potentiometry ion-specific electrodes prevents misdiagnosis and inappropriate therapy. Early identification of pseudohyponatremia further emphasizes the crucial role of the laboratory in ensuring accurate interpretation and optimizing patient management.
Authors
- Macarena Calvente de Rávena
- María Ortiz-Espejo
- F. Pons-Vidal
Institutions
- Marqués de Valdecilla University Hospital (ES)
- Sociedad Española de Medicina de Familia y Comunitaria (ES)
Publication Details
- Journal
- Diagnosis
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1515/dx-2025-0150
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00