Multicenter Study on the Safety and Efficacy of First-Line Nivolumab-Combination Chemotherapy in Patients Aged 75 Years and Older with Unresectable Advanced or Recurrent Gastric Cancer

First-line chemotherapy with nivolumab is safe and effective in patients aged ≥75 years with a good performance status, as in younger patients, suggesting that it is a valid treatment option for the former subgroup.

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Publication Details

Journal
Oncology
Published
2026-01-12
DOI
https://doi.org/10.1159/000550345
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Multicenter Study on the Safety and Efficacy of First-Line Nivolumab-Combination Chemotherapy in Patients Aged 75 Years and Older with Unresectable Advanced or Recurrent Gastric Cancer

Nobuhiro Nakazawa, Hisashi Shimizu, Hisashi Hosaka, Kengo Kasuga et al.
Oncology
Gastric Cancer Management and Outcomes
article

Multicenter Study on the Safety and Efficacy of First-Line Nivolumab-Combination Chemotherapy in Patients Aged 75 Years and Older with Unresectable Advanced or Recurrent Gastric Cancer

Nobuhiro Nakazawa, Hisashi Shimizu, Hisashi Hosaka, Kengo Kasuga, Yuji Kumakura, Kenji Nakazato, Naritaka Tanaka, Toshiki Yamashita, Daisuke Yoshinari, Akiharu Kimura, Kyoichi Ogata, Akihiko Sano, Takuhisa Okada, Takuya Shiraishi, Kana Saito, Hiroshi Saeki, Ken Shirabe, Yasunari Ubukata
article en

Abstract

First-line chemotherapy with nivolumab is safe and effective in patients aged ≥75 years with a good performance status, as in younger patients, suggesting that it is a valid treatment option for the former subgroup.

Oncology
Gunma University (JP), Maebashi Red Cross Hospital (JP), National Hospital Organization Takasaki Medical Center (JP), Japanese Red Cross Kochi Hospital (JP), Japan Community Healthcare Organization (JP), National Hospital Organization (JP), Fuji Heavy Industries Health Insurance Society Ota Memorial Hospital (JP), Isesaki Fukushima Hospital (JP), Hyogo Prefectural Cancer Center (JP), Isesaki Municipal Hospital, Toto (Japan) (JP)
Good health and well-being
Openalex Percentile: Top 91%
Gastric Cancer Management and Outcomes
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Multicenter Study on the Safety and Efficacy of First-Line Nivolumab-Combination Chemotherapy in Patients Aged 75 Years and Older with Unresectable Advanced or Recurrent Gastric Cancer — Nobuhiro Nakazawa, Hisashi Shimizu, et al. · Oncology (2026) | TGRS Research Map | TGRS