Sex-based differences in outcomes following endovascular therapy for anterior circulation large vessel occlusion: a pooled analysis of DEVT, RESCUE BT, and MARVEL trials

This pooled analysis demonstrated that no statistically significant differences were observed between men and women in clinical or safety outcomes following EVT for anterior circulation LVO. Furthermore, there was no evidence of interaction between sex and predefined subgroups in terms of treatment effect modification for EVT outcomes.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-12
DOI
https://doi.org/10.3389/fneur.2025.1753257
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Sex-based differences in outcomes following endovascular therapy for anterior circulation large vessel occlusion: a pooled analysis of DEVT, RESCUE BT, and MARVEL trials

Yangyang Duan, Zhenxuan Tian, LiLan Wang, Gaoming Li et al.
Frontiers in Neurology
Acute Ischemic Stroke Management
article

Sex-based differences in outcomes following endovascular therapy for anterior circulation large vessel occlusion: a pooled analysis of DEVT, RESCUE BT, and MARVEL trials

Yangyang Duan, Zhenxuan Tian, LiLan Wang, Gaoming Li, L Y Li, GW Liu, W X Li, M B. Chen, Xu Xu, Jie Yang, Chawen Ding, Xu Xu, Lisi Zhang, Haoxuan Zhu, Binghan Wang, Yuhan Fan, Nizhen Yu, Boyu Chen, Dahong Yang, Chengsong Yue, Xiaolei Shi, Shitao Fan, Shihai Yang, Yihui Yang, Zhixi Wang, Wenzhe Sun, Zhuang Li
article en

Abstract

This pooled analysis demonstrated that no statistically significant differences were observed between men and women in clinical or safety outcomes following EVT for anterior circulation LVO. Furthermore, there was no evidence of interaction between sex and predefined subgroups in terms of treatment effect modification for EVT outcomes.

Frontiers in NeurologyVol. 16
Army Medical University (CN), Dalian Medical University (CN), Second Affiliated Hospital of Chongqing Medical University (CN), People's Liberation Army 401 Hospital (CN), Xinqiao Hospital (CN), Chinese People's Liberation Army (CN), Hainan Medical University (CN), Chongqing Medical University (CN)
National Natural Science Foundation of China, Army Medical University
Good health and well-being
Openalex Percentile: Top 91%
Acute Ischemic Stroke Management
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