Psychotropic medication use and risks of kidney injury and fall-related events: a propensity score–matched cohort study

Psychotropic medication use was associated with modest but significantly higher long-term risks of kidney injury and fall-related events in a large real-world cohort, even after accounting for underlying psychiatric and neurologic conditions. These findings support the need for integrated renal monitoring and injury-prevention strategies in patients receiving long-term psychotropic therapy.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-01-12
DOI
https://doi.org/10.3389/fphar.2025.1690792
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Psychotropic medication use and risks of kidney injury and fall-related events: a propensity score–matched cohort study

Po-Hsun Hou, Yu-Hsien Wu, S. R. Huang, Shang-Feng Tsai
Frontiers in Pharmacology
Dialysis and Renal Disease Management
article

Psychotropic medication use and risks of kidney injury and fall-related events: a propensity score–matched cohort study

Po-Hsun Hou, Yu-Hsien Wu, S. R. Huang, Shang-Feng Tsai
article en

Abstract

Psychotropic medication use was associated with modest but significantly higher long-term risks of kidney injury and fall-related events in a large real-world cohort, even after accounting for underlying psychiatric and neurologic conditions. These findings support the need for integrated renal monitoring and injury-prevention strategies in patients receiving long-term psychotropic therapy.

Frontiers in PharmacologyVol. 16
National Yang Ming Chiao Tung University (TW), National Chung Hsing University (TW), Tunghai University (TW), Taipei Veterans General Hospital (TW), Taichung Veterans General Hospital (TW), Keelung Chang Gung Memorial Hospital (TW), National Defense Medical Center (TW)
Shanghai Educational Development Foundation
Good health and well-being
Openalex Percentile: Top 92%
Dialysis and Renal Disease Management
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Psychotropic medication use and risks of kidney injury and fall-related events: a propensity score–matched cohort study — Po-Hsun Hou, Yu-Hsien Wu, et al. · Frontiers in Pharmacology (2026) | TGRS Research Map | TGRS