Conservative vs. surgical management of acute appendicitis in children with acute leukemia: a single-center retrospective case series

This small case series highlights that managing acute appendicitis in leukemic children requires individualized MDT-guided strategies. Conservative treatment was effective for uncomplicated cases, while TSSDPLA provided a feasible minimally invasive option for complications. Early resumption of chemotherapy was prioritized. All patients achieved infection control and continued leukemia therapy without mortality. These findings offer a preliminary management framework, pending validation in larger studies.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-01-12
DOI
https://doi.org/10.3389/fped.2025.1722697
Primary Topic
Appendicitis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Conservative vs. surgical management of acute appendicitis in children with acute leukemia: a single-center retrospective case series

Meng Kong, Jinhua Jia, Meng Shi, Chuanyang Liu et al.
Frontiers in Pediatrics
Appendicitis Diagnosis and Management
article

Conservative vs. surgical management of acute appendicitis in children with acute leukemia: a single-center retrospective case series

Meng Kong, Jinhua Jia, Meng Shi, Chuanyang Liu, Hongzhen Liu
article en

Abstract

This small case series highlights that managing acute appendicitis in leukemic children requires individualized MDT-guided strategies. Conservative treatment was effective for uncomplicated cases, while TSSDPLA provided a feasible minimally invasive option for complications. Early resumption of chemotherapy was prioritized. All patients achieved infection control and continued leukemia therapy without mortality. These findings offer a preliminary management framework, pending validation in larger studies.

Frontiers in PediatricsVol. 13
Shandong University (CN), Jinan Maternity And Care Hospital (CN), Fourth People’s Hospital of Jinan (CN), Shandong Provincial Hospital (CN)
Openalex Percentile: Top 92%
Appendicitis Diagnosis and Management
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