High‐Resolution Diffusion‐MRI Detects Degeneration in Hippocampal Subregions after Neurotrauma in 3xTg‐AD Mice
Our results demonstrate that the hippocampal CA1/CA3 subregions are more vulnerable to neurotrauma. This finding may help clarify the mechanisms underlying trauma-accelerated AD and suggest that advanced diffusion-MRI is a potential tool for the early diagnosis of trauma patients at risk of developing AD.
Authors
- Juliet A. Moncaster (ORCID: https://orcid.org/0000-0002-7849-4325)
- D. Parsons (ORCID: https://orcid.org/0000-0001-6553-0262)
- Ning Hua (ORCID: https://orcid.org/0000-0002-8549-3056)
- Elijah Demb
- Lee E Goldstein
- Olga Minaeva
Institutions
- Boston University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_107226
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00