Reducing agents for induction and maintenance therapy achieve long-term remission of refractory ulcerative colitis: A case report and review of literature

STS and RDLA are reducing agents that serve as highly effective and safe therapy for the induction and maintenance of remission in UC, even in patients refractory or poorly controlled by conventional and advanced therapies. Should preliminary findings be validated by subsequent clinical trials, the use of reducing agents could potentially prevent thousands of colectomies and represent a paradigm shift in the treatment of UC.

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Publication Details

Journal
World Journal of Gastroenterology
Published
2026-01-12
DOI
https://doi.org/10.3748/wjg.v32.i2.114222
Primary Topic
Inflammatory Bowel Disease
Type
article
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article

Reducing agents for induction and maintenance therapy achieve long-term remission of refractory ulcerative colitis: A case report and review of literature

Pamela B. Sylvestre
World Journal of Gastroenterology
Inflammatory Bowel Disease
article

Reducing agents for induction and maintenance therapy achieve long-term remission of refractory ulcerative colitis: A case report and review of literature

Pamela B. Sylvestre
article en

Abstract

STS and RDLA are reducing agents that serve as highly effective and safe therapy for the induction and maintenance of remission in UC, even in patients refractory or poorly controlled by conventional and advanced therapies. Should preliminary findings be validated by subsequent clinical trials, the use of reducing agents could potentially prevent thousands of colectomies and represent a paradigm shift in the treatment of UC.

World Journal of GastroenterologyVol. 32(2)
Cincinnati Children's Hospital Medical Center (US), University of Cincinnati Medical Center (US)
Good health and well-being
Openalex Percentile: Top 91%
Inflammatory Bowel Disease
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