Nonlinear association between pre-pregnancy body mass index and preterm birth in singleton pregnancies conceived with assisted reproductive technology

A nonlinear association between pre-pregnancy BMI and PTB was observed in women treated with ART. Lower and higher BMIs were associated with an increased risk of PTB, respectively, with the optimal pre-pregnancy BMI associated with the lowest risk of PTB being approximately 21.6 kg/m<sup>2</sup>. The lowest point may vary depending on whether there was a previous termination or fetal loss.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-01-12
DOI
https://doi.org/10.3389/fnut.2025.1651462
Primary Topic
Gestational Diabetes Research and Management
Type
article
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article

Nonlinear association between pre-pregnancy body mass index and preterm birth in singleton pregnancies conceived with assisted reproductive technology

Tingting Zhuang, Jingli Sun, Yu Zhang
Frontiers in Nutrition
Gestational Diabetes Research and Management
article

Nonlinear association between pre-pregnancy body mass index and preterm birth in singleton pregnancies conceived with assisted reproductive technology

Tingting Zhuang, Jingli Sun, Yu Zhang
article en

Abstract

A nonlinear association between pre-pregnancy BMI and PTB was observed in women treated with ART. Lower and higher BMIs were associated with an increased risk of PTB, respectively, with the optimal pre-pregnancy BMI associated with the lowest risk of PTB being approximately 21.6 kg/m<sup>2</sup>. The lowest point may vary depending on whether there was a previous termination or fetal loss.

Frontiers in NutritionVol. 12
General Hospital of Shenyang Military Region (CN), Jinzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 92%
Gestational Diabetes Research and Management
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