Case Report: Prolonged DAWS in an RLS patient under severe relational stress
This case illustrates that DAWS can occur in RLS patients even at low DA doses, with atypical symptoms possibly involving autonomic and central sensitization. Relational stress may significantly exacerbate symptom severity, potentially leading to profound neurological destabilization through mechanisms such as cross-system hypersensitivity or a kindling-like process, as suggested by existing literature. This factor may need to be systematically assessed in DAWS management. As a rare patient-authored account, this report contributes to the understanding of DAWS in non-PD populations and highlights the need for longitudinal research to guide safer withdrawal protocols and integrated care.
Authors
- M. Gillon
Institutions
- University of Liège (BE)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fnhum.2025.1613710
- Primary Topic
- Restless Legs Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds De La Recherche Scientifique - FNRS