Trastuzumab deruxtecan (DS-8201) plus bevacizumab for HER2-low metastatic breast cancer with malignant pleural effusion: a case report and literature review

To our knowledge, this is the first reported case of DS-8201 plus bevacizumab for HER2-low metastatic breast cancer with malignant pleural effusion. This case highlights the potential of this regimen as a promising therapeutic option for patients with limited alternatives.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-12
DOI
https://doi.org/10.3389/fonc.2025.1694553
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Trastuzumab deruxtecan (DS-8201) plus bevacizumab for HER2-low metastatic breast cancer with malignant pleural effusion: a case report and literature review

Jiannan Liu, Hao Han, Jing Liu, Ping Sun et al.
Frontiers in Oncology
HER2/EGFR in Cancer Research
article

Trastuzumab deruxtecan (DS-8201) plus bevacizumab for HER2-low metastatic breast cancer with malignant pleural effusion: a case report and literature review

Jiannan Liu, Hao Han, Jing Liu, Ping Sun, Miaomiao Yang, Congcong Wang
article en

Abstract

To our knowledge, this is the first reported case of DS-8201 plus bevacizumab for HER2-low metastatic breast cancer with malignant pleural effusion. This case highlights the potential of this regimen as a promising therapeutic option for patients with limited alternatives.

Frontiers in OncologyVol. 15
Weifang Medical University (CN), Yuhuangding Hospital (CN), Second Hospital of Shandong University (CN)
Good health and well-being
Openalex Percentile: Top 91%
HER2/EGFR in Cancer Research
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