Incorporating parenchymal heterogeneity into FLIS to improve MRI-based liver function assessment

FLIS has no reported correlation with elastography-based liver fibrosis staging. Parenchymal heterogeneity is not included as a parameter in the standard FLIS. Integrating heterogeneity improves correlation with fibrosis stage and clinical scores. FLIS-H enables fast, reliable, structure-function liver assessment in clinical radiology.

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Publication Details

Journal
Insights into Imaging
Published
2026-01-12
DOI
https://doi.org/10.1186/s13244-025-02187-z
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Incorporating parenchymal heterogeneity into FLIS to improve MRI-based liver function assessment

Muhammet Selman Söğüt, Afak Durur Karakaya, Hande Özen Atalay
Insights into Imaging
Hepatocellular Carcinoma Treatment and Prognosis
article

Incorporating parenchymal heterogeneity into FLIS to improve MRI-based liver function assessment

Muhammet Selman Söğüt, Afak Durur Karakaya, Hande Özen Atalay
article en

Abstract

FLIS has no reported correlation with elastography-based liver fibrosis staging. Parenchymal heterogeneity is not included as a parameter in the standard FLIS. Integrating heterogeneity improves correlation with fibrosis stage and clinical scores. FLIS-H enables fast, reliable, structure-function liver assessment in clinical radiology.

Insights into ImagingVol. 17(1)
Koç University (TR), Türk Anesteziyoloji ve Reanimasyon Derneği (TR)
Openalex Percentile: Top 90%
Hepatocellular Carcinoma Treatment and Prognosis
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